Ceftriaxone Sodium Sterile
Ceftriaxone Sodium Sterile
Ceftriaxone Sodium Sterile Manufacturers in India, RAL ( Rajasthan Antibiotics Ltd.) produces, distributes, and exports a wide range of premium pharmaceutical APIs all over the world. RAL ( Rajasthan Antibiotics Ltd.) is the leading manufacturers of ceftriaxone sodium sterile active pharmaceutical ingredient (API), formulations along with analytical services in and outside India. We have a strong client database India and all over the globe.All of our APIs and intermediates are produced in FDA-approved, top-notch, cutting-edge manufacturing facilities that follow cGMP standards.
RAL-Life ( Rajasthan Antibiotics Ltd.) is largest Ceftriaxone Sodium Sterile Manufacturers in India. RAL-Life ( Rajasthan Antibiotics Ltd.) is a fast growing integrated pharmaceutical company which commenced its commercial production in 1991 and has increased in both size and stature to become one of the country’s largest producers of the Sterile API’s (Active Pharmaceutical Ingredients). Besides being the first company in India to produce Ampicillin Sodium Sterile, RAL-Life ( Rajasthan Antibiotics Ltd.) also pioneered the manufacturing of Sterile Anti-Ulcer drugs namely Omeprazole Sodium Sterile and Pantaprazole Sodium Sterile for which it has won worldwide acceptance. RAL ( Rajasthan Antibiotics Ltd.) established the Manufacturing of Ceftriaxone Sodium Sterile in India, for which it has won universal recognition. The Company has a well-established clientele in India as well as all over the globe.
| C18H17N8NaO7S3 | |
|---|---|
 |
|
| CAS No. | 7081-44-9 |
| HSN Code | 29419090 |
| Standard packs include 1 kg, 2 kg, 4 kg, 5 kg, and 10 kg (or) dependent on the needs of the customer. | |
Ceftriaxone sodium sterile Manufacturers in India
Regarding sterile sodium ceftriaxone:
ceftriaxone sodium sterile good quality developed under cautious and safe supervision of research and development expert team in compliance with all regulations. Developed HVAC system that covers all production activities from the beginning production to the final packaging and storage of the product. Ral Life is also provide customized solutions and services as per needs of our clients.
Ceftriaxone Sodium Sterile is a potent antibiotic used for the treatment of a variety of bacterial infections. It belongs to the class of third-generation cephalosporins, which are known for their broad-spectrum antibacterial activity against a wide range of gram-positive and gram-negative bacteria.
Ceftriaxone Sodium Sterile is an injectable form of the antibiotic, which is administered through intravenous or intramuscular injection. It is commonly used in hospitals and other healthcare facilities for the treatment of serious infections, such as meningitis, sepsis, and pneumonia, among others.
RAL is a well-known, internationally recognised maker of Specialty Chemicals and Pharmaceuticals in India. Pharmaceutical APIs, formulations, and other products are made from chemicals that we produce.
Explore the mechanism of action, pharmacokinetics, indications, dosing, and side effects of Ceftriaxone Sodium Sterile in detail.
Mechanism of Action:
Ceftriaxone Sodium Sterile works by inhibiting bacterial cell wall synthesis, which is essential for the survival and growth of bacteria. It achieves this by binding to the penicillin-binding proteins (PBPs) present in the bacterial cell wall, thereby inhibiting the transpeptidation and cross-linking of peptidoglycan chains, which are critical steps in cell wall synthesis.
As a result, the bacterial cell wall becomes weak and unstable, leading to cell lysis and death. Ceftriaxone Sodium Sterile is active against a broad range of gram-positive and gram-negative bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, Neisseria gonorrhoeae, and many others.
Pharmacokinetics:
Ceftriaxone Sodium Sterile is available as a powder for injection, which is reconstituted with sterile water or saline solution prior to use. The drug is administered through intravenous or intramuscular injection, and its pharmacokinetics vary depending on the route of administration.
When administered intravenously, Ceftriaxone Sodium Sterile is rapidly distributed throughout the body, with a volume of distribution of approximately 7-12 L. The drug is highly protein-bound (95%) and is primarily excreted through the kidneys.
The half-life of Ceftriaxone Sodium Sterile is approximately 8 hours, and the drug is eliminated from the body mainly through renal excretion, with a clearance rate of approximately 10-20 mL/min.
Indications:
Ceftriaxone Sodium Sterile is indicated for the treatment of a wide range of bacterial infections, including:
- Community-acquired pneumonia
- Meningitis
- Septicemia
- Urinary tract infections
- Gonorrhea
- Lyme disease
- Otitis media
- Skin and soft tissue infections
- Intra-abdominal infections
Dosing:
The dosing of Ceftriaxone Sodium Sterile varies depending on the age, weight, and severity of the infection being treated. The drug is typically administered through intravenous or intramuscular injection once or twice a day, depending on the severity of the infection.
The recommended dose for adults and children over 12 years of age is 1-2 grams of Ceftriaxone Sodium Sterile per day, administered once or twice daily. The maximum daily dose should not exceed 4 grams.
For children under 12 years of age, the recommended dose is based on the child’s weight, with a maximum daily dose of 80 mg/kg/day.
| The most common side effects of Ceftriaxone Sodium Sterile | |
|---|---|
| Like all antibiotics, Ceftriaxone Sodium Sterile can cause side effects, although not everyone who uses the drug will experience them. The most common side effects of Ceftriaxone Sodium Sterile include: | Headache |
| Vomiting | |
| Pain, swelling, or redness at the injection site | |
| Diarrhoea | |
| Dizziness | |
| Fever |
In rare cases, Ceftriaxone Sodium Sterile can cause serious side effects, such as:
- Anaphylaxis: a severe allergic reaction that can cause difficulty breathing, swelling of the face, throat, or tongue, and a rapid or weak pulse.
- Clostridium difficile-associated diarrhea (CDAD): a type of diarrhea caused by the overgrowth of the bacterium Clostridium difficile in the colon. This can occur during or after treatment with antibiotics and can be severe and life-threatening.
- Pseudomembranous colitis: an inflammatory condition of the colon characterized by the formation of a membrane-like layer of inflammatory cells and fibrin on the colon’s surface. This can also be caused by the overgrowth of Clostridium difficile and can be severe and life-threatening.
It is essential to report any side effects or adverse reactions to Ceftriaxone Sodium Sterile to a healthcare professional immediately.
Drug Interactions:
Ceftriaxone Sodium Sterile can interact with other medications, including:
- Warfarin: Ceftriaxone Sodium Sterile can increase the risk of bleeding when taken with warfarin, a blood thinner.
- Calcium-containing solutions: Ceftriaxone Sodium Sterile should not be mixed with calcium-containing solutions, as this can lead to the formation of a precipitate in the injection solution.
- Other antibiotics: Ceftriaxone Sodium Sterile should not be administered with other antibiotics that are known to cause cross-reactivity, such as penicillins, as this can increase the risk of an allergic reaction.
FAQ about Ceftriaxone Sodium Sterile
What is Ceftriaxone Sodium Sterile?
Ceftriaxone Sodium Sterile is a broad-spectrum antibiotic used to treat a variety of bacterial infections. It works by inhibiting bacterial cell wall synthesis, which is essential for the survival and growth of bacteria.
What conditions are treated with Ceftriaxone Sodium Sterile?
Ceftriaxone Sodium Sterile is used to treat a wide range of bacterial infections, including meningitis, septicemia, pneumonia, urinary tract infections, and many others.
How is Ceftriaxone Sodium Sterile administered?
Ceftriaxone Sodium Sterile is available as a powder for injection and is administered through intravenous or intramuscular injection.
What is the dosage for Ceftriaxone Sodium Sterile?
The dosing of Ceftriaxone Sodium Sterile varies depending on the age, weight, and severity of the infection being treated. It is essential to follow the dosing instructions provided by the healthcare professional.
What are the side effects of Ceftriaxone Sodium Sterile?
Common side effects of Ceftriaxone Sodium Sterile include nausea, vomiting, diarrhea, headache, and rash. In rare cases, it can cause severe allergic reactions, including anaphylaxis. It can also cause Clostridium difficile-associated diarrhea (CDAD) and pseudomembranous colitis.
Can Ceftriaxone Sodium Sterile interact with other medications?
Yes, Ceftriaxone Sodium Sterile can interact with other medications, including warfarin, calcium-containing solutions, and other antibiotics that are known to cause cross-reactivity, such as penicillins.
Is Ceftriaxone Sodium Sterile safe during pregnancy and breastfeeding?
Ceftriaxone Sodium Sterile is generally considered safe to use during pregnancy and breastfeeding, but it is essential to discuss the risks and benefits with a healthcare professional before using the drug.
Can Ceftriaxone Sodium Sterile be used in children?
Yes, Ceftriaxone Sodium Sterile can be used in children, but the dosing varies depending on the age, weight, and severity of the infection being treated.
How should Ceftriaxone Sodium Sterile be stored?
Ceftriaxone Sodium Sterile should be stored at room temperature, away from light and moisture. It should be kept out of the reach of children.
Do I need a prescription to use Ceftriaxone Sodium Sterile?
Yes, Ceftriaxone Sodium Sterile is a prescription medication and should only be used under the guidance of a healthcare professional.
Registered Office
222A, 2nd Floor
Hemkunt Chambers, 89,
Nehru Place, New Delhi-110019
Corporate Office
M 134 , 2nd Floor, Opp.
Super Bazar, Connaught Place,
New Delhi – 110001