Azithromycin sodium sterile Manufacturers in India

Regarding sterile sodium azithromycin :

Indications

Azithromycin sodium sterile is used to treat a variety of bacterial infections, including:

1.  Respiratory tract infections: Azithromycin sodium sterile is used to treat respiratory tract infections caused by susceptible bacteria, including community-acquired pneumonia, acute exacerbations of chronic obstructive pulmonary disease (COPD), and sinusitis.
2. Skin and soft tissue infections: Azithromycin sodium sterile is used to treat skin and soft tissue infections caused by susceptible bacteria, including cellulitis, impetigo, and erysipelas.
3. Sexually transmitted infections: Azithromycin sodium sterile is used to treat sexually transmitted infections caused by susceptible bacteria, including chlamydia and gonorrhea.
4. Gastrointestinal infections: Azithromycin sodium sterile is used to treat gastrointestinal infections caused by susceptible bacteria, including traveler’s diarrhea and enteric fever.

Dosage and Administration

Azithromycin sodium sterile is available in both oral and intravenous formulations. The dosage and administration of the medication depend on the patient’s age, weight, and the severity of the infection.

• Oral formulation: Azithromycin sodium sterile is available in tablet and liquid formulations for oral administration. Adults are advised to take 500 mg once daily for three days. For children, the recommended dosage is 10 mg/kg once daily for three days.
• Intravenous formulation: Azithromycin sodium sterile is available as a sterile powder for intravenous administration. The recommended dosage for adults is 500 mg once daily for two days, followed by 500 mg once weekly for the remaining three weeks of treatment. For children, the recommended dosage is 10 mg/kg once daily for two days, followed by 10 mg/kg once weekly for the remaining three weeks of treatment.

Contraindications

In patients with a known allergy to azithromycin or any macrolide antibiotic, azithromycin sodium sterile is contraindicated. It should also be used with caution in patients with liver or kidney disease, as it can cause hepatotoxicity and nephrotoxicity.

Adverse Effects

The most common adverse effects of azithromycin sodium sterile include:

1. Gastrointestinal effects: Diarrhea, nausea, vomiting, and abdominal pain are common adverse effects of azithromycin sodium sterile.
2. Allergic reactions: Hypersensitivity reactions, including rash, hives, and anaphylaxis, have been reported with azithromycin sodium sterile use.
3. Hepatotoxicity: Azithromycin sodium sterile can cause liver damage, especially in patients with pre-existing liver disease.
4. Nephrotoxicity: Azithromycin sodium sterile can cause kidney damage, especially in patients with pre-existing kidney disease.
5. Cardiac effects: Azithromycin sodium sterile can prolong the QT interval, leading to ventricular arrhythmias.

Drug Interactions

Azithromycin sodium sterile can interact with other medications, including:

• Antacids: Antacids containing aluminum or magnesium can decrease the absorption of azithromycin sodium sterile.
• Warfarin: Azithromycin sodium sterile can increase the effects of warfarin, leading to bleeding.
• Digoxin: Azithromycin sodium sterile can increase the levels of digoxin in the blood, leading to toxicity
• Cyclosporine: Azithromycin sodium sterile can increase the levels of cyclosporine in the blood, leading to toxicity.
• Theophylline: Azithromycin sodium sterile can increase the levels of theophylline in the blood, leading to toxicity.
• Statins: Azithromycin sodium sterile can increase the risk of muscle toxicity when taken with statins.
• Ergot derivatives: Azithromycin sodium sterile can increase the risk of ergotism when taken with ergot derivatives.
• CYP3A4 inhibitors: Azithromycin sodium sterile can interact with medications that inhibit CYP3A4, such as ketoconazole and erythromycin, leading to increased azithromycin levels in the blood and increased risk of adverse effects.

Pregnancy and Lactation

Azithromycin sodium sterile is classified as pregnancy category B, indicating that it is generally safe to use during pregnancy. However, it should be used with caution, especially during the first trimester.

Azithromycin sodium sterile is excreted in breast milk and can be passed to the nursing infant. Consequently, lactating mothers should use it with caution.

Conclusion

Azithromycin sodium sterile is a commonly used antibiotic medication that is effective against a wide range of bacterial infections. It is available in both oral and intravenous formulations and is used in various clinical settings, including hospitals, clinics, and community pharmacies. The medication is generally well-tolerated, but it can cause adverse effects, especially in patients with pre-existing liver or kidney disease. Azithromycin sodium sterile can also interact with other medications, and caution should be exercised when co-administering it with other drugs. Patients should always consult their healthcare provider before taking any medication, including azithromycin sodium sterile.